FORTUNE — Apparently some really smart people have trouble mastering Microsoft Office.
Early Wednesday morning, in an e-mail that went out to reporters around 2 A.M., Harvard professors Carmen Reinhart and Kenneth Rogoff copped to making an Excel error in their research paper tying high levels of government debt to low levels of growth. The paper, “Growth in Time of Debt,” has become a powerful data point for those who argue against government spending even to revive the economy — Congressman Paul Ryan cited it in his most recent budget — and is the basis for the two professors’ best-selling book This Time is Different.
Related: Latest study doesn’t settle the growth and debt debate
When it comes to Excel, though, Reinhart and Rogoff aren’t all that different. Wall Streeters can relate. Prominent financial blogger James Kwak calls Excel “one of the greatest, most powerful, most important software applications of all time.” But perhaps we ask too much of the program, or perhaps of our ability to cut and paste. In the past few years, Excel has been implicated in some of the biggest blunders on Wall Street and in finance in general. Here are some notable Excel victims:
Kenneth Rogoff

Amherst researchers. In fact, the economies grew 2.2%.
London Whale

MF Global

Barclays purchase of Lehman Brothers

Utah

Fannie Mae

Native Americans
