• Home
  • News
  • Coins2Day 500
  • Tech
  • Finance
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia
Healthoverdose

Overdose deaths in the U.S. hit record 107,000 last year, CDC says

By
Mike Stobbe
Mike Stobbe
and
The Associated Press
The Associated Press
Down Arrow Button Icon
By
Mike Stobbe
Mike Stobbe
and
The Associated Press
The Associated Press
Down Arrow Button Icon
May 11, 2022, 11:13 AM ET
Syringes and vials of Naloxone are shown during the media tour of the supervised drug injection site OnPoint, in New York on November 30, 2021. More than 107,000 Americans died of drug overdoses in 2021, according to the CDC.
Syringes and vials of Naloxone are shown during the media tour of the supervised drug injection site OnPoint, in New York on November 30, 2021. More than 107,000 Americans died of drug overdoses in 2021, according to the CDC.Yuki Iwamura—AFP/Getty Images

More than 107,000 Americans died of drug overdoses last year, setting another tragic record in the nation’s escalating overdose epidemic, the Centers for Disease Control and Prevention estimated Wednesday.

The provisional 2021 total translates to roughly one U.S. Overdose death every 5 minutes. It marked a 15% increase from the previous record, set the year before. The CDC reviews death certificates and then makes an estimate to account for delayed and incomplete reporting.

Dr. Nora Volkow, director of the National Institute on Drug Abuse, called the latest numbers “truly staggering.”

U.S. Overdose deaths have risen most years for more than two decades. The increase began in the 1990s with overdoses involving opioid painkillers, followed by waves of deaths led by other opioids like heroin and—most recently—illicit fentanyl.

Last year, overdoses involving fentanyl and other synthetic opioids surpassed 71,000, up 23% from the year before. There also was a 23% increase in deaths involving cocaine and a 34% increase in deaths involving meth and other stimulants.

Overdose deaths are often attributed to more than one drug. Some people take multiple drugs and inexpensive fentanyl has been increasingly cut into other drugs, often without the buyers’ knowledge, officials say.

“The net effect is that we have many more people, including those who use drugs occasionally and even adolescents, exposed to these potent substances that can cause someone to overdose even with a relatively small exposure,” Volkow said in a statement.

Experts say the COVID-19 pandemic has exacerbated the problem as lockdowns and other restrictions isolated those with drug addictions and made treatment harder to get.

Overdose death trends are geographically uneven. Alaska saw a 75% increase in 2021—the largest jump of any state. In Hawaii, overdose deaths fell by 2%.

Sign up for the Coins2Day Features email list so you don’t miss our biggest features, exclusive interviews, and investigations.

About the Authors
By Mike Stobbe
See full bioRight Arrow Button Icon
By The Associated Press
See full bioRight Arrow Button Icon
Rankings
  • 100 Best Companies
  • Coins2Day 500
  • Global 500
  • Coins2Day 500 Europe
  • Most Powerful Women
  • Future 50
  • World’s Most Admired Companies
  • See All Rankings
Sections
  • Finance
  • Leadership
  • Success
  • Tech
  • Asia
  • Europe
  • Environment
  • Coins2Day Crypto
  • Health
  • Retail
  • Lifestyle
  • Politics
  • Newsletters
  • Magazine
  • Features
  • Commentary
  • Mpw
  • CEO Initiative
  • Conferences
  • Personal Finance
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Coins2Day Brand Studio
  • Coins2Day Analytics
  • Coins2Day Conferences
  • Business Development
About Us
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Coins2Day
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map

© 2025 Coins2Day Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Coins2Day Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.