• Home
  • Latest
  • Coins2Day 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia
HealthMark Cuban

Mark Cuban’s upstart online pharmacy just scored a big win by teaming with one of California’s biggest health insurers

By
John Tozzi
John Tozzi
,
Fiona Rutherford
Fiona Rutherford
and
Bloomberg
Bloomberg
Down Arrow Button Icon
By
John Tozzi
John Tozzi
,
Fiona Rutherford
Fiona Rutherford
and
Bloomberg
Bloomberg
Down Arrow Button Icon
August 17, 2023, 7:47 PM ET
 Mark Cuban.
Mark Cuban. Rocky Widner/NBAE via Getty Images

CVS Health shares tumbled after Blue Shield of California, one of the state’s largest health insurers, said it would drop the company’s Caremark unit as its main pharmacy benefit manager. 

Recommended Video

The insurer, a nonprofit, said Thursday it expects to save as much as $500 million a year by switching to a group of companies including Amazon.com Inc. And an upstart from billionaire Mark Cuban. It’s the biggest win yet for those newcomers trying to upend the existing prescription benefits system, and if it works could provide a blueprint for other insurers and employers to follow.

The goal is to change the incentives for prescription benefits managers, distributors and pharmacies, said Paul Markovich, chief executive of Blue Shield of California. “They make more revenue and they make more profit when we sell a higher volume of more expensive drugs,” he said in an interview. “We just need to start over in terms of thinking about this system.”

News of the high-profile experiment sent shares of dominant PBMs down sharply: CVS shares fell 8.1% as of trading close Thursday, its most since October, while rival Cigna Group fell 6.4%.

The Wall Street Journal earlier reported the change-up.

Blue Shield may face challenges replacing one vendor for PBM services with five, some with competing interests. “We’re skeptical this approach is sophisticated enough and practical, yet it bears watching,” Bloomberg Intelligence analysts Jonathan Palmer and Jordan Dahan said in a note. 

The insurer is also not dropping CVS entirely, as Caremark will continue to process more expensive specialty drugs, a profitable and growing market for PBMs.

Tapping Newcomers

Companies that provide health benefits have long bemoaned their lack of visibility into how much drug middlemen pay and charge for medications. The California insurer’s move will test whether it can assemble an alternative supply chain involving a mix of companies new to the pharmacy benefits business alongside established suppliers.

Amazon, the retail giant whose greater penetration into the drug supply chain has been dreaded by pharmacy benefit managers and drugstore chains, will offer at-home drug delivery. Mark Cuban’s Cost Plus Drugs Co. Will provide access to low-cost medications, and Abarca Health will process drug claims, Blue Shield of California said. 

The plan will also rely on Prime Therapeutics, a pharmacy benefits manager operated by a group of Blue Cross Blue Shield plans, to negotiate savings with drug manufacturers.

Using services from several new companies to provide drug benefits may be challenging, but if the regional health insurer is successful, others may follow, according to analysts at Evercore ISI.

Some are more skeptical. The selloff “overstates” the impact of the decision, TD Cowen analyst Charles Rhyee wrote, adding: “We don’t believe the BSCA decision will have a long-term impact on the PBM model.”

CVS affirmed its earnings guidance for 2023 and said the partial loss of the contract would have an “immaterial impact” on the company’s long-term outlook.

Broken Incentives

Blue Shield of California spends about $4 billion a year on drugs, Markovich said, and the company estimates it can save 10% to 15% of that through this new model. Some of the savings will come from removing incentives that favor high-cost drugs over less expensive alternatives.

For example, he said, the insurer struggled to get CVS to cover a less expensive version of a prostate cancer drug called abiraterone that would cut the price  to $160 from about $3,000. “They initially refused and they kept refusing” for months, he said. “It’s like pulling teeth to get that to happen.”

CVS gets generic drugs through an existing joint venture and medications must meet certain standards, a company representative said in an email. Some health plans that invested in a new generic drug manufacturer called CivicaScript sought to dispense those products through an outside pharmacy, and CVS is working with them to do it, the representative said. Blue Shield of California is participating in CivicaScript.

Markovich said the insurer’s 7,500 employees would first see the new arrangement in 2024, and it will offer it to some clients who may be interested. In 2025, the change will be effective across its lines of business for commercial and government health plans.

Profit Impact

The loss could dent CVS’s 2025 earnings by 2 to 6 cents a share, the Evercore analysts estimated. About half of the insurer’s annual drug spend is likely to be retained by CVS in its specialty pharmacy business, they said. 

“We look forward to providing care for Blue Shield of California’s members who require complex, specialty medications – as we have for nearly two decades,” a CVS spokesperson said in an email.

Markovich said CVS might have been a strong contender if Blue Shield wanted to continue with a traditional PBM, but he said the company is aiming for a broader change.

“This issue is a systemic one,” he said. “All of the pharmacy benefits managers operate this way in this system, and they have no financial interest in changing it.”

Join us at the Coins2Day Workplace Innovation Summit May 19–20, 2026, in Atlanta. The next era of workplace innovation is here—and the old playbook is being rewritten. At this exclusive, high-energy event, the world’s most innovative leaders will convene to explore how AI, humanity, and strategy converge to redefine, again, the future of work. Register now.
About the Authors
By John Tozzi
See full bioRight Arrow Button Icon
By Fiona Rutherford
See full bioRight Arrow Button Icon
By Bloomberg
See full bioRight Arrow Button Icon

Latest in Health

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Coins2Day Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Coins2Day Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Coins2Day Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Coins2Day Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Coins2Day Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Coins2Day Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Coins2Day Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Coins2Day Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Coins2Day Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Coins2Day Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Coins2Day Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Coins2Day Editors
October 20, 2025
Rankings
  • 100 Best Companies
  • Coins2Day 500
  • Global 500
  • Coins2Day 500 Europe
  • Most Powerful Women
  • Future 50
  • World’s Most Admired Companies
  • See All Rankings
Sections
  • Finance
  • Leadership
  • Success
  • Tech
  • Asia
  • Europe
  • Environment
  • Coins2Day Crypto
  • Health
  • Retail
  • Lifestyle
  • Politics
  • Newsletters
  • Magazine
  • Features
  • Commentary
  • Mpw
  • CEO Initiative
  • Conferences
  • Personal Finance
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Coins2Day Brand Studio
  • Coins2Day Analytics
  • Coins2Day Conferences
  • Business Development
About Us
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Coins2Day
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Most Popular

placeholder alt text
Commentary
Yes, you're getting a bigger tax refund. Your kids won't thank you for the $3 trillion it's adding to the deficit
By Daniel BunnJanuary 26, 2026
2 days ago
placeholder alt text
Personal Finance
Current price of silver as of Tuesday, January 27, 2026
By Joseph HostetlerJanuary 27, 2026
1 day ago
placeholder alt text
Success
Despite running $75 billion automaker General Motors, CEO Mary Barra still responds to ‘every single letter’ she gets by hand
By Preston ForeJanuary 26, 2026
2 days ago
placeholder alt text
Personal Finance
Current price of silver as of Monday, January 26, 2026
By Joseph HostetlerJanuary 26, 2026
2 days ago
placeholder alt text
Economy
An unusual Fed ‘rate check’ triggered a free fall in the U.S. dollar and investors are fleeing into gold
By Jim EdwardsJanuary 26, 2026
2 days ago
placeholder alt text
Success
As AI wipes out desk jobs, Citigroup CEO Jane Fraser says the company is training 175,000 employees to ‘reinvent themselves’ before their roles change forever
By Emma BurleighJanuary 27, 2026
1 day ago

© 2026 Coins2Day Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Coins2Day Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.


Latest in Health

succession
SuccessFamily
How not to say that thing you’ll regret forever: 3 rules for family conversations about money 
By Glenn KurlanderJanuary 28, 2026
3 hours ago
reem
Commentaryhunger
How to fight child hunger in a time of foreign aid cuts
By Reem Alabali Radovan, Rajiv J. Shah and Mads Krogsgaard ThomsenJanuary 28, 2026
7 hours ago
People walk outside of a WeWork office building in London.
Future of WorkOffice Culture
Amazon and JPMorgan led the Coins2Day 500 in returning to the office 5 days a week. Now they’re leading a coworking comeback
By Jacqueline MunisJanuary 27, 2026
20 hours ago
Healthbeauty
5 Best Red Light Therapy Panels of 2026: Personally Tested
By Christina SnyderJanuary 27, 2026
20 hours ago
Graphic reads: Coins2Day Titans and Disruptors of Industry with Albert Bourla, CEO of Pfizer, Hosted by Alyson Shontell (both pictured).
C-SuiteCoins2Day 500: Titans and Disruptors of Industry
Pfizer CEO Albert Bourla stared down the COVID-19 pandemic. Now he has his eyes set on cancer 
By Coins2Day EditorsJanuary 27, 2026
1 day ago
Palantir CEO Alex Karp during an interview at the 2026 World Economic Forum in Davos, Switzerland.
InnovationImmigration
Palantir/ICE connections draw fire as questions raised about tool tracking Medicaid data to find people to arrest
By Tristan BoveJanuary 26, 2026
2 days ago