Top 5 NAD Boosters: 2025 Picks

TL;DR

• Omre NMN+Resveratrol is the top overall NAD+ supplement choice for 2025.
• Wonderfeel Youngr NMN is recommended as the best NAD+ supplement for women.
• ProHealth NMN Pro Powder 1000 is the premier choice for an NAD+ powder supplement.
• Nutricost NAD+ is highlighted as the best NAD+ supplement option for men.

A certified nutrition coach assisted us in assessing and choosing the premier NAD+ supplements for 2025, presenting a compilation of options supported by clinical evidence and third-party testing, suitable for both novice and experienced NAD+ users.

Best NAD+ Supplements of 2025

• Best NAD+ Supplement Overall: Omre NMN+Resveratrol
• Best NAD+ Supplement for Women: Wonderfeel Youngr NMN
• Best Powder NAD+ Supplement: ProHealth NMN Pro Powder 1000
• Best NAD+ Supplement for Men: Nutricost NAD+
• Best NAD+ Supplement for Energy: Innerbody Labs NAD+ Support

Why Trust Coins2Day

Our expert testers have evaluated numerous top-selling supplements currently available, employing our thorough supplement testing methodology to find the best products for all folks.

Top NAD+ Supplements Reviewed

Omre NMN + Resveratrol is the top NAD+ supplement choice.

Our Perspective on Omre NMN + Resveratrol

Omre NMN + Resveratrol stands out as our top choice for an NAD+ supplement, featuring clinically validated amounts of both NMN and micronized trans-resveratrol. These ingredients synergize to enhance NAD+ synthesis and promote better cellular function. Additionally, the formula incorporates BioPerine, a black pepper extract, which could further aid in absorption. Collectively, these elements may contribute to increased energy levels and cognitive function, while potentially mitigating the aging process. 

Our reviewer, Pete, tried Omre NMN + Resveratrol and was instantly impressed by its stylish packaging and gold label. He also noted the clear instructions, awarding the supplement a perfect score of 5/5 for both initial appeal and user-friendliness. “Just take two capsules daily in the morning with food, or as recommended by your healthcare professional,”, he stated. 

After scrutinizing the pills and taking his first dose, Pete deducted a few points for swallowability, giving the supplement a 3 out of 5 in this category. “It’s an average-size clear capsule with an off-white powder inside,” he said. “The capsule is about 1 inch in length and 1 cm in diameter. It has no taste.” That said, he awarded it a 5 for side effects and said he experienced no unwanted outcomes after consuming the capsules. 

Pete appreciated how transparent the website and label is on this product, and the 99% purity of the ingredients. “The supplement contains 500 mg of NMN powder, 500 mg of resveratrol, and 5 mg of Bioperine black pepper extract,” he said. “Both the NMN and resveratrol are designed to support healthy aging, and Bioperine is added to enhance the absorption of the resveratrol. The website says the product is third-party tested and they provide Certificates of Analysis on the site.”

That level of purity and transparency, however, comes at a cost. Pete's primary criticism of Omre NMN + Resveratrol was its price point, which averages about $2 per serving. While not the priciest NAD+ supplement among those we evaluated, he did mention it's not the most budget-friendly option available. 

Wonderfeel Youngr NMN: Best NAD+ for Women

Wonderfeel Youngr NMN: Our Take

Wonderfeel Younger NMN stands out as the top NAD+ supplement for women, featuring clinically validated doses of NMN, resveratrol, ergothioneine, and other ingredients designed to boost cellular energy and combat aging. This supplement was developed by a Harvard physician with extensive experience, spanning almost three decades, in NAD+ research and creation. Wonderfeel openly shares its third-party testing results, and the product is also vegan, gluten-free, and non-GMO, produced in the USA within CGMP-certified facilities.

While this isn’t necessarily a gender-specific product, we found it to be a good option for women due to the metabolic effects and reduction in energy we tend to experience from perimenopause onward. This product has a powerful 900mg dose of NMN, plus other research-backed ingredients like resveratrol and antioxidants.

Tester Gwen awarded the product a perfect score of 5 for its initial presentation. “The container is designed to look like a pill, which I think is cute,” she commented. “I also like that it’s small enough to fit easily in my bag.” Furthermore, Gwen found the directive to take two pills each morning straightforward, assigning another 5 to the supplement for this aspect. 

Certified nutrition coach Pete, our tester, also found the formula appealing, noting its substantial NMN content and other components. “The full two-capsule serving size contains 1,000 mg of NMN,” he commented. Human studies typically employ doses ranging from 250 to 500 mg daily, placing this product's dosage higher. However, research has explored doses up to 1,200 mg/day without significant adverse reactions. Following his consumption of two capsules, he experienced no discernible side effects, awarding the supplement an additional 5 for this aspect. 

Pete's primary reservation regarding this supplement concerns its cost. While Pete rated Wonderfeel a 1 out of 5, this score reflects its standing among all supplements evaluated. At $1.73 per serving, Wonderfeel's pricing is competitive within the NAD+ supplement market tested, with other options costing between 73 cents and over $3 per serving. Considering its dosage and formulation, we believe it offers good value. 

ProHealth NMN Pro Powder is the top choice for an NAD+ supplement in powder form.

ProHealth NMN Pro Powder: Our View

ProHealth NMN Pro Powder 1000 earned our top spot for NAD+ powder supplements. Its formula's purity, independent testing, and straightforward application resonate with individuals prioritizing transparency and simplicity. This drink's powder form is ideal for those avoiding pills and is said to enhance absorption and bioavailability. We found it to be a reliable daily supplement for bolstering metabolism, energy, endurance, and cognitive function.  

Tester Kate noted the powder's container had a “clean and classy” look. She awarded the item a perfect score of 5 for initial appeal and how simple the directions were. “It says to take one to two scoops a day,”, she commented. “The directions are easy to find and are listed out on the back of the bottle.” 

Kate found that mixing powders can sometimes be challenging, but she easily dissolved ProHealth NMN's powder in a 10ml glass of water in under a minute, achieving a smooth consistency. She commented, "“It dissolved really well!”" and further complimented its texture, awarding it a perfect score of 5 out of 5 for mixability. “There are no visible chunks or grittiness. It really just looks like water.”

The mixture's flavor, however, only received a 3 out of 5 rating. “It is very, very sweet,” Kate reported a similar sweet lingering taste after consuming the powder, but she encountered no other adverse reactions or stomach problems. “It has a strong pineapple and mango flavor to it, which isn’t my favorite. My other tester didn’t mind the sweetness so I really think this would be a personal preference for the taste.” She stated. “I actually had a great amount of energy after taking it,” 

Ultimately she reported an overall positive experience with the product. “I would recommend this for someone who is not looking for a budget-friendly NAD+ product,” she said. “But I loved the packaging and the quality of the product, so it does make sense for this price point.” 

Nutricost NAD+ is the top NAD+ supplement choice for men.

Our Perspective on Nutricost NAD+

Nutricost NAD+ stands out as our top choice for an NAD+ supplement for men, featuring a simple, unadorned formula and a potent 1,000 mg dose per serving. While its health advantages aren't exclusive to any gender, men might find its uncomplicated makeup especially appealing. It's also suitable for vegans, free from gluten, and produced in a facility that's NSF Certified, GMP compliant, and FDA registered. Furthermore, with 60 servings per bottle, you'll need to restock less often.

Pete evaluated Nutricost's NAD+ supplement, giving it a perfect score of 5 out of 5 for his initial assessment. “It’s a white plastic bottle with a blue screw top lid that opens and closes easily. The label has a matte finish that’s easy to read. The container is small enough to be travel friendly,” he commented. The instructions were straightforward and user-friendly, earning a 5 out of 5 rating from Pete in this aspect. 

Pete rated Nutricost's NAD+ swallowability at a 3 out of 5. He described the standard-sized capsules, measuring approximately one inch long and one centimeter wide, as clear with a white powder filling. While the recommended daily intake is two capsules, Pete found them somewhat difficult to swallow. However, he noted that during his testing, the capsules were both tasteless and odorless, which he considered a positive aspect. 

After trying these NAD+ supplements a few times, he didn’t experience any side effects, rating it a 5 out of 5 in this category. Though, he didn’t necessarily feel immediate benefits either. 

Our team also loved the dosage this product provides. Nutricost’s NAD provides 1,000 milligrams of NAD per serving, which is large compared to other options. “This is a higher dosage than most NAD supplements on the market,” Pete said. “They’re typically between 250 and 500 milligrams per serving.”

Innerbody Labs NAD+ Support for Energy

A Look at Innerbody Labs' NAD+ Support

Innerbody Labs NAD+ Support stands out as our top choice for an NAD+ Supplement for Energy due to its multi-faceted approach to targeting cellular metabolism. This supplement incorporates both NMN (700 milligrams) and NR (400 milligrams), effectively supporting the body's NAD+ pathways that are crucial for powering cellular energy. Scientific studies indicate that increasing NAD+ levels can contribute to activate sirtuins and enhance mitochondrial function, both of which are vital for sustained energy and endurance.

Gwen gave Innerbody’s NAD+ Support a perfect 5 out of 5 for her initial assessment. “The container for this product is incredibly sleek and simple,” she commented. “I love the clean white background and the pops of red. I also like that it’s not overly cluttered with information on the front.” Furthermore, Gwen found the supplement's facts to be straightforward and simple to grasp, awarding it a 5 out of 5 for clarity and adherence to instructions.

She rated the swallowability a 3 out of 5: “The capsule is a standard size, I wouldn’t say that it’s too large or difficult to swallow,” Gwen said. “The serving size is three capsules, though. This isn’t problematic for me because I’m used to taking a bunch of supplements, but some folks may need to take the pills individually,” she said. If you prefer fewer pills per serving, we recommend you go with Nutricost NAD.

Gwen didn’t notice any taste with this product. “It doesn’t taste chalky or have any kind of aftertaste that I noticed,” she said, rating it a 5 out of 5 for taste. She didn’t experience any side effects or digestive upset, either.

What are NAD+ Supplements?

Nicotinamide adenine dinucleotide (NAD+) is a vital coenzyme present in every living cell, essential for converting nutrients into usable energy (ATP) and maintaining proper cellular function. It plays critical roles in DNA repair, gene expression, metabolism, and cell signaling, all of which are central to energy production and longevity. However, NAD+ levels naturally decline with age, oxidative stress, and unhealthy lifestyle factors, leading to decreased metabolic and cognitive function and faster cellular aging. 

NAD+ supplements are designed to assist in restoring these diminishing amounts. The majority of offerings don't include NAD+ directly but rather precursor compounds (such as nicotinamide riboside [NR], nicotinamide mononucleotide [NMN], or niacin) which are transformed into NAD+ inside the body. This action elevates cellular NAD+ and amplifies mitochondrial energy output. Through restoring NAD+ equilibrium, these supplements can potentially aid in maintaining energy, sharpening concentration, and promoting more effective cellular restoration processes.

What is the function of NAD+ Supplements within the body?

NAD+ supplements function at the cellular level within your body, aiding in energy restoration, tissue repair, and enhanced metabolic resilience. Although not a universal remedy, keeping NAD+ levels healthy could lead to increased vitality and a longer lifespan through reduced oxidative stress.

Our Approach to Identifying and Choosing Top NAD+ Supplements

We tested and evaluated NAD+ supplements and scored them on a scale of 1-5 for factors such as first impressions, easy-to-follow directions, swallowability, side effects, and value. Our testers evaluate the products based on their own individual experiences and preferences. We then review their testing feedback and data to share our findings and recommendations with you.

Formula

To pick and evaluate NAD+ supplements, we partnered with a certified nutrition coach to confirm each formulation adheres to stringent efficacy and safety benchmarks. Our assessment method prioritizes clinically validated dosages aligned with contemporary scientific findings, searching for NAD+ products providing the ideal quantities demonstrated in scholarly articles. We place significant emphasis on the caliber and openness of ingredients, preferring NAD+ supplements produced in GMP-certified environments, subjected to independent verification, and devoid of superfluous components.

Taste and Texture

Flavor is a big part of our testing process. We asked our testers to provide feedback on the taste, aftertaste, and swallowability of the NAD+ supplements.

Form

Serving sizes for NAD+ supplements range from a single capsule to multiple pills. Whenever possible, we chose NAD+ products that required fewer capsules per serving for added convenience. We also tested NAD+ supplements in various forms, such as a mixable powder and face cream, for folks who like to vary the way they ingest the supplement.

Third-Party Testing

We selected NAD+ supplements that have been verified through third-party testing for safety, purity, and label accuracy. This process also screens for harmful substances like heavy metals and pesticides.

Athletes require third-party testing to verify the absence of prohibited substances, making sport certification for products vital. As the FDA doesn't oversee supplements, independent validation is key for ensuring safety, correctness, and public confidence.

Value

When evaluating worth, we prioritize brands that obtain their components domestically and possess accreditations, like Informed Choice.

Discovering the Ideal NAD+ Supplement for Your Needs

Your individual requirements for NAD+ supplements will depend on factors such as your age, daily habits, and any particular health objectives you're pursuing concerning energy levels or cellular maintenance.

Consider these factors when choosing the most suitable NAD+ supplement for you.

Your Body’s Needs

While NAD+ supplements may aid in bolstering energy metabolism and cellular repair, they're not a universal requirement. Consider them an optional enhancement to existing healthy practices—such as balanced nutrition, physical activity, and adequate rest—rather than a fundamental pillar of well-being.

Formula

Given that individuals have unique dietary requirements, it's advisable to review the ingredients prior to buying. Certain NAD+ formulations may contain added vitamins, collagen, or other beneficial substances, which could suit different dietary plans or fitness objectives. Should a supplement offer extra nutrients, cross-reference them with your suggested daily intake levels (RDVs) to prevent overconsumption. Selecting a product that enhances your current nutritional intake can maximize the benefits of your NAD+ supplement.

Cost

It's common to take NAD+ supplements each day, and their cost can add up, so think about your finances before you buy. Products with fewer artificial sweeteners or additives might be more expensive due to their superior quality and how their ingredients are obtained.

Third-Party Testing

Since the FDA doesn't oversee supplements, independent testing by third parties offers confirmation of a NAD+ supplement's safety, purity, and accurate labeling. This verification guards against issues such as incorrect labeling, contamination, or prohibited substances, fostering trust in your selected products. Such independent evaluation is vital for guaranteeing both the quality and safety of the product.

Benefits of NAD+ Supplements

Similar to a NMN supplement or collagen powder, NAD+ supplements might provide a range of health advantages, possibly aiding your longevity and metabolic well-being. Consider these examples:

• Enhanced energy production: NAD+ helps to combat fatigue and improve endurance at the cellular level by converting nutrients into usable energy
• Improved cognitive and cellular health: NAD+ supports brain health by protecting neurons from oxidative stress and inflammation, promoting better memory, mental clarity, and overall cognitive function
• Metabolic and anti-aging support: Maintaining optimal NAD+ levels has been linked to better metabolic regulation, improved insulin sensitivity, reduced inflammation, and protection against age-related decline

How to Take NAD+ Supplements

NAD+ supplements are commonly available as capsules, tablets, powders, or liquids, usually consumed on a daily basis. To achieve optimal outcomes: 

• Consume NAD+ supplements in the morning, ideally with or following your breakfast to enhance absorption and provide sustained energy.
• Start with the lowest recommended dose and increase gradually
• Consistency is key; regular daily use maintains steady NAD+ levels
• You can combine NAD+ supplements with ingredients such as resveratrol or TMG to enhance their effects, though we advise consulting your physician about potential interactions with medications and suitable combinations prior to initiating or mixing supplements.

What's the Recommended Daily NAD Dosage?

Clinical research suggests that the optimal daily intake for NAD+ boosters, including nicotinamide riboside or nicotinamide mononucleotide, generally ranges from 250 to 500 milligrams daily for the majority of adults, with certain research employing up to 1,000mg daily to achieve more significant boosts in NAD+ concentrations.

What are the potential dangers of consuming NAD+ supplements?

Most individuals find NAD+ supplements to be safe and easily tolerated, though some may experience slight adverse effects like nausea, headaches, minor digestive issues, flushing, or tiredness. However, there are potential risks: the long-term safety of NAD+ supplementation, particularly at high doses or over extended durations, remains under investigation. NAD+ supplements could potentially interact with certain medications or existing health issues, so consulting your physician prior to beginning any NAD+ regimen is advised.

Frequently Asked Questions

Which NAD+ supplement is best?

Omre NMN + Resveratrol is our best NAD+ supplement pick. NMN is a precursor to NAD, helping your body produce more of the coenzyme naturally. We also like that this formula includes resveratrol, a natural compound that acts as an antioxidant, offering anti-inflammatory properties.

What is the most effective form of NAD+?

Precursors to NAD+, such as NMN and NR, are an effective form of NAD+. Taking NAD+ supplements, whether in capsule, powder, or another form, is also effective at maintaining the level of NAD+ in your body when taken consistently.

Is NAD just vitamin B3?

No, NAD+ isn't Vitamin B3, although they share similarities. Nicotinamide riboside, which leads to NAD+, is a type of Vitamin B3.